This thread is re. antibiotic resistance. It explains why sometimes stronger & stronger antibiotics are used for persistant infections.Thx. to all who contributed.
Does this make any sense to anyone? Is it correct?
"Unfortunately, with bacterial films, the antibiotics only kill some of the bacteria, while other bacteria within the film are not only resistant, but somehow use the action of the antibiotic to prosper and protect the other bacteria types within the colony. They act as a community to thwart any antibiotics. So, from what I understand, c diff isn't a type of bacteria, but a group that live and work together."
The statement you read is just a round about way of describing general bacterial resistance. As far as I know, this phenomenon is not really unique to cdiff, but is the action of alot of bacterial colonies.
It's been going on since the first bacteria appeared on this earth, and will continue to do so indefinitely. You can liken it to Darwin's "survival of the fittest" theory.
Every single time an antibiotic is administered for any infection, there will be a number of bacteria that survive the attack....and thus the need for stronger antibiotics that work by different mechanisms to kill or disable them in future. This is not necesssarily an important occurence within one host, but is meaningful for the general population as a whole.
Antibiotics...the drugs designed to stop bacteria in their tracks, actually enhance their ability to survive for the long haul.
I read this in a book I was recently reading which I posted and recommended on the site. It's a bit freaky but here goes.
If you stay on one antibiotic for a longer than a normal period of time, the "bugs" inside of you will become resistant to not only that antibiotic but to numerous antibiotics even if you have never actually taken those antibiotics. This is not only the case w/ C-diff but with all bugs that are inside of us. For example, most of us probably have some form of E.Coli inside of us whether or not it is making us sick (just like C-diff) is another story.
I'll use myself just as an example. I got C-diff from being on Doryx (doxycycline) for three years for acne. Because I was on Doryx for those three years if I am carrying any strain of E.Coli it most likely would be not only resistant to the antibiotic used to treat E.Coli but it would also become resistant to other antibiotics as well. Most cases of long term single antibiotic use have produced bacteria inside of the host that is resistant to as many as 6 different antibiotics even though that host never even took those antibiotics. So if my E.Coli became resistant to say the Doryx (I don't even know if it's used for E.Coli, but I'll just explain it using that) which I'm sure it has, if I carry it then it is almost guaranteed that the E.Coli also became resistant to many multiple antibiotics as well. Basically, I could be in serious trouble.
This does not seem to be a "given" in people who use different short term antibiotic treatments although it can and does occur.
I found it quite scary but also amazing that this happens. My son spent two solid years on Omnicef when he was younger so I often wonder about him as well. It makes sense then why the first treatments for C-diff and most other bacterial infections start off with short term course of antibiotics . Who knows it may be the reason why my C-diff strain is resistant to Flagyl and also Xifaxan. Two antibiotics that I have never touched previously in my life.