I ralpased 5 weeks post Vanco on Thursday got my test result back today, Toxin B is positive. At my request my family Dr prescribed Dificid 200mg 2/day for 10days. I will have my first pill later today around 8:00 PM.
How is Difcid? Is it easy to tolerate? I hear vomiting is a common side affect? My pharmacist has been working at my local pharmacy for 17 years she is normally very knowledgeable but this was first time she was giving out a Difcid , she didn’t know much about it
When I first was diagnosed, I took Flagyl for 8 days and then switched to Vanco. Flagyle was awful, but Vanco was easy to tolerate and unlike Flagyl I dint have any side effect while on Vanco .
Starting Dificid today
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Starting Dificid today
Last edited by Ali-Mar on Sun Apr 26, 2020 8:00 pm, edited 1 time in total.
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
Hi
I don't feel well on Dificid. The first round (10 days) went well for me 5 years ago. This time I just don't feel well and have alot of pelvic pressure which I had POST Vanco 5 years ago. I think Dificid is harsher to take but is works. I have the nausea but no vomiting.
I would speak with your GI about a taper which would require another prescription when you complete the 10 days. We have had MANY on the site that have been cured with Dificid including me 5 years ago after months and months of Vanco.
It works and I have very happy you are on it! I am currently in the taper, still don't feel well.....that will come in time.
Wishing you the best with it
NanciT
I don't feel well on Dificid. The first round (10 days) went well for me 5 years ago. This time I just don't feel well and have alot of pelvic pressure which I had POST Vanco 5 years ago. I think Dificid is harsher to take but is works. I have the nausea but no vomiting.
I would speak with your GI about a taper which would require another prescription when you complete the 10 days. We have had MANY on the site that have been cured with Dificid including me 5 years ago after months and months of Vanco.
It works and I have very happy you are on it! I am currently in the taper, still don't feel well.....that will come in time.
Wishing you the best with it
NanciT
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Re: Starting Dificid today
I felt like horrible the first 7 day on it. Nausea was terrible. I had to pair it with phenergan. I would just start to lessen the nausea and have to take another pill. I think did vomit on it the first 2 days in the mornings. Stool got worse as well for the first 7 days. By day 7 some of my energy came back. Like I could get off the couch for 10 min better. I never did achieve solid stools while taking it so there that. I did go down to one a day though from my 3 a day. By day 10 my flu like symptoms subsided. This was my main symptoms with the c diff. I was not feeling well before taking so I dont know if that added to it. Took it first round for c diff and now I think 9 weeks out. It been a long healing of the 9 weeks so give it time again. I questioned it half way though treatment because I thought I would be better right away but I gave it time things changed slowly.
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Re: Starting Dificid today
Thanks you NancyT and Spike for your replies and good wishes
Do you take it with food?
What do u do if you vomit , do you continue taking it?
The pharmacist was telling me if I vomit within 30 mins of taking it I have to take another one and ask my doctor to write another prescription to make up for the lost dose
Do you take it with food?
What do u do if you vomit , do you continue taking it?
The pharmacist was telling me if I vomit within 30 mins of taking it I have to take another one and ask my doctor to write another prescription to make up for the lost dose
Last edited by Ali-Mar on Sun Apr 26, 2020 9:36 pm, edited 1 time in total.
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
I would vomit right after I got up and was managed to keep the pill down. I was horribly nauseated before being treated as a side of effected of c diff and this lessens over time with treatment. I also took it with the most food I could hold down. Most the time it was a bagel or animal cracker.
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Re: Starting Dificid today
When I had CDIFF 5 years ago I had vomiting this was for the year including 5 relapses, it didnt matter what I was taking.
I did not vomit after taking Dificid , it did not cause me to vomit, but the nausea is terrible. I wear Sea Bands all day. I do always take it after I have eaten, some days that is not much. Now that I am on every other day it's improving. It is VERY expensive and was a battle for me to get this taper from my insurance.
NanciT
I did not vomit after taking Dificid , it did not cause me to vomit, but the nausea is terrible. I wear Sea Bands all day. I do always take it after I have eaten, some days that is not much. Now that I am on every other day it's improving. It is VERY expensive and was a battle for me to get this taper from my insurance.
NanciT
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Re: Starting Dificid today
Thank you, hopefully this will work
Last edited by Ali-Mar on Sun Apr 26, 2020 10:06 pm, edited 1 time in total.
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
Yes it is very expensive I heard it is over $1K for 20 bills. My copay was $50 so it wasn’t so bad, I think i am allowed for a refill if necessary
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
So sorry that you ended up relapsing! I did a Dificid taper/pulse that has been successful so far (6 weeks out). I actually felt really good in general on Dificid, much better than I had on Flagyl 9 years ago. The only real bothersome side effect of Dificid that I can point to is that I've been having what are probably occasional bladder spasms/discomfort; this started a few weeks after ending the Dificid.
Hoping Dificid does the trick for you! I would request a followup taper if possible to do after the usual 10 days are up. My doctor did say that nausea was common with Dificid and prescribed me an anti-nausea drug, but I didn't have to take it.
Hoping Dificid does the trick for you! I would request a followup taper if possible to do after the usual 10 days are up. My doctor did say that nausea was common with Dificid and prescribed me an anti-nausea drug, but I didn't have to take it.
2011: contracted c-diff after taking Amoxicillin and Cipro. Successfully treated with Flagyl taper. (Posts under old username, Elvish)
2020: contracted c-diff after taking Augmentin. Finished Dificid taper/pulse on 3/15.
2020: contracted c-diff after taking Augmentin. Finished Dificid taper/pulse on 3/15.
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Re: Starting Dificid today
Thanks Elvish,
Did u do Vanco first before Difcid ?``````
How long did it take on Difcid when you noticed some improvement?
What are the dosage of the taper? One per day for 7 days and 1 every other day for 26 days?
I had my fist pill one hour so far no noticeable side effects - thanks god
Did u do Vanco first before Difcid ?``````
How long did it take on Difcid when you noticed some improvement?
What are the dosage of the taper? One per day for 7 days and 1 every other day for 26 days?
I had my fist pill one hour so far no noticeable side effects - thanks god
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
Hi Ali-Mar,
I followed the same pattern as you. Flagyl. Vanco. And then Dificid. I just finished my 10 days of Dificid on Sunday (so two days ago). Honestly I felt great on Dificid. My symptoms started improving after the first full day of pills and all symptoms had disappeared within about 5 days of taking the pills. I suffered no side effects. Good luck to you. Where I have just finished my pills I am of course a bit nervous but hopeful that the third time was the charm! Let me know how you make out.
I followed the same pattern as you. Flagyl. Vanco. And then Dificid. I just finished my 10 days of Dificid on Sunday (so two days ago). Honestly I felt great on Dificid. My symptoms started improving after the first full day of pills and all symptoms had disappeared within about 5 days of taking the pills. I suffered no side effects. Good luck to you. Where I have just finished my pills I am of course a bit nervous but hopeful that the third time was the charm! Let me know how you make out.
32 y/o female. Got C. diff in Feb. 2020. Prescribed Flagyl (10 days), then Flagyl again (4 days), then Vanco (10 days), then Dificid (10 days), then Dificid again (10 days), then a Vanco taper (5 wks), then a Dificid taper (2 mths) and finally recovered.
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Re: Starting Dificid today
Hi NS789,
That is great, hope Dificid will get you though this awful bug.
I finished my 2nd full day and I already feel so much better (fingers crossed). I am thinking of asking for 20 more pils and doing the taper? Was is your thought?
How long after Vanco did you relapse? For me it was 5 weeks post Vanco
That is great, hope Dificid will get you though this awful bug.
I finished my 2nd full day and I already feel so much better (fingers crossed). I am thinking of asking for 20 more pils and doing the taper? Was is your thought?
How long after Vanco did you relapse? For me it was 5 weeks post Vanco
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
I'm glad you're feeling better! I had fast results too.
I thought about asking for a Dificid taper but I decided to try the standard/recommended 10 days first. If I relapse and need a second round of Dificid (god forbid), I will ask to do a taper at that time.
The 10 days of Dificid pills were also quite pricey (even with a plan!), which is another reason I decided to give the standard 10-day course a try.
I relapsed within about 7 or 8 days of finishing Vanco. But I should mention that I was only given 10 days of Vanco and I'm not sure it was enough to get rid of the c diff. It seems like most people are prescribed 14 days. So I wonder if that's why it failed in my case.
I thought about asking for a Dificid taper but I decided to try the standard/recommended 10 days first. If I relapse and need a second round of Dificid (god forbid), I will ask to do a taper at that time.
The 10 days of Dificid pills were also quite pricey (even with a plan!), which is another reason I decided to give the standard 10-day course a try.
I relapsed within about 7 or 8 days of finishing Vanco. But I should mention that I was only given 10 days of Vanco and I'm not sure it was enough to get rid of the c diff. It seems like most people are prescribed 14 days. So I wonder if that's why it failed in my case.
32 y/o female. Got C. diff in Feb. 2020. Prescribed Flagyl (10 days), then Flagyl again (4 days), then Vanco (10 days), then Dificid (10 days), then Dificid again (10 days), then a Vanco taper (5 wks), then a Dificid taper (2 mths) and finally recovered.
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Re: Starting Dificid today
Yes, i was also prescribed 10 day Vanco but 4 pils per day. I agree most people take it for 14 days.
How are you doing now post Dificid are you back to regular formed BM? Any signs of PI-IBS?
How are you doing now post Dificid are you back to regular formed BM? Any signs of PI-IBS?
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020
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Re: Starting Dificid today
I am doing well so far. I am finally having formed BMs (which I never 'achieved' on Flagyl or Vanco) and no IBS symptoms yet (though it's still early days...).
I should mention that I'm also taking Florastor and eating probiotic yogurt twice a day to get some good bacteria back in my system.
I should mention that I'm also taking Florastor and eating probiotic yogurt twice a day to get some good bacteria back in my system.
32 y/o female. Got C. diff in Feb. 2020. Prescribed Flagyl (10 days), then Flagyl again (4 days), then Vanco (10 days), then Dificid (10 days), then Dificid again (10 days), then a Vanco taper (5 wks), then a Dificid taper (2 mths) and finally recovered.
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