Pulse Dosing

Treatments, possible treatments, unsubstantiated/unproven treatments. Consult your doctor first.
Guest

Postby Guest » Sun Sep 30, 2001 9:29 am

Dave - you're right about going on and off the medicine. But I think I saw someplace in here that in addition to doing that, you're reducing the dose you take on the "on" days. That's what scares me - didn't work for me (and I tried everything). My suspicion is that the reason it didn't work is because a reduced dose on the "on" days isn't enough to kill the spores that hatch when you're "off". But now I don't see your message about reducing the dose any more. These new boards drive me nuts. <BR><BR>[Guest Posted by: 'Lauren']

Guest

Postby Guest » Mon Oct 01, 2001 5:30 pm

DaveF - I found it! You had written in your "withdrawal from vanco" note that you were reducing your dose as you were pulse dosing. It was the dose reduction that scared me - not the pulsing. Sorry if I was confusing. <BR><BR>[Guest Posted by: 'Lauren']

Guest

Postby Guest » Mon Oct 01, 2001 10:15 pm

hi! <BR>what exactly is "colitis"??? thanks! <BR><BR>[Guest Posted by: 'william']

Guest

Postby Guest » Fri Oct 05, 2001 1:56 am

William, <BR> <BR>Colitis is inflammation of the large intestine (colon). Symptoms may include abdominal pain, diarrhea,dehydration, abdominal bloating, increased intestinal gas, and bloody stools. <BR> <BR>Colitis may be identified on flexible sigmoidoscopy or colonoscopy (a flexible tube is inserted in the rectum and the colon is evaluated) and biopsies may show changes of inflammation. <BR> <BR>Colitis may result in bleeding, ulceration & perforation. <BR> <BR> <BR>Sam <BR>Admin <BR><BR>[Guest Posted by: 'Admin']

Guest

Postby Guest » Fri Oct 05, 2001 9:35 am

This is in reference to what William asked concerning what is Colitis? All of the symptoms that Sam described are exactly what's been going on with me except no bleeding. The pain was horrible when it hit. All symptoms have disappeared with a week of Flagl. But, sorry I'm going to have to get a little graphic. My stools are covered and I mean covered in mucas. It's more mucas than stool. This is really concerning me and don't know if it's normal while all of this is trying to clear up or if I should call my doctor. I just don't want to overeact. Can anyone tell me? I'm still bloated but feel so much better.- Thanks <BR><BR>[Guest Posted by: 'Lee']

Guest

Postby Guest » Fri Oct 05, 2001 12:07 pm

Lee, <BR> <BR>How long has it been since you've seen your doc? It is common to have large amounts of mucous with C. Diff... especially when you have just started to recover. <BR> <BR>Keep in mind that complications can lead to IBS as well. Your doc should be able to diagnose if you are getting something other than c. diff. Be sure to keep an eye out for degrading symptoms - fever, bleeding, more pain, vomiting/nausea, etc.. <BR> <BR>Be very careful with what you eat - this is one of the most critical factors in getting better. <BR> <BR>Good luck and stay under close watch with your doctor and do what he or she says, <BR> <BR>Sam <BR><BR>[Guest Posted by: 'Admin']

Guest

Postby Guest » Fri Oct 05, 2001 12:43 pm

Sam, <BR> <BR>Thanks for the info. Here'e my deal and would love to know what you think. I had the diarreah for 17 days with the bloating, gas, pain but no blood and a small fever off and on. I've been on the Flagyl for a week today and have gotten better every day. As for eating, Dr. told me to eat whatever I wanted when I felt I could. I eased my way back into it and have eaten whatever all week. Sam, I feel great and am hopeful that I'm getting over it but then I see this mucus and hear these stories and I jsut want to know what is normal and what isn't. Haven't seen the doctor in a week and he told me not to worry with a f-up appointment unless I didn't "feel" better. Any advice as I want to be proactive and smart about all of this! Thanks <BR><BR>[Guest Posted by: 'Lee']

Guest

Postby Guest » Sat Oct 06, 2001 12:40 am

Lee & William, <BR>Don't expect things to return to "normal" after having C. diff. It really does a number on your gut. "Bad days" are normal for quite a while. Some people wind up with IBS after C. diff. It's not fun -- but better than C. diff. All mucuous really means is irritation. And C. diff. does irritate in many ways! <BR> <BR>I'd just ignore those symptoms, and if they persist for several weeks, contact your doctor. For years after I got over active C. diff., I also had terrible stomach pains but haven't had them for a long time. I found a heating pad worked wonders. As long as you feel better generally, you are most likely on that long road to recovery. Give yourself time to heal. <BR><BR>[Guest Posted by: 'Bobbie']

Guest

Postby Guest » Sat Oct 06, 2001 4:59 pm

Couldn't have said it better than Bobbie just did. <BR><BR>[Guest Posted by: 'Admin']

Guest

Postby Guest » Sat Oct 06, 2001 8:39 pm

Reply for Lauren's post, way down the page... <BR> <BR>Yes, I did reduce the dosage. Oh geez, I was confusing. I reduced the dosage per day of pulsing because I was having side-effects from the Vanco. You may see another post I started about the side effects I had (oral Vanco was systemic for ME, which is very rare). <BR> <BR>My doctor ordered me to reduce the dosage along with the pulsing because of the side effects I was having of neurological problems related to absorbing the Vanco systemically. This is very, very rare, so please nobody use me as an example. In my specific case, the doctor did many tests, all negative for cdiff, but with the side effects, he warned me to cut it down. <BR> <BR>As usual, my body is not normal! He said it was the first time he ever saw anybody have systemic effects of orally given Vanco. <BR> <BR>But let me add, for any newcomers... Vanco seems to have worked and gotten rid of my symptoms. And the side effects have all gone away now. So thank goodness for this medicine... and again, I have to say thank goodness for this site! <BR> <BR>Thanks Lauren. <BR><BR>[Guest Posted by: 'DaveF']

Guest

Postby Guest » Sat Oct 06, 2001 9:12 pm

Dave - gotcha. Now I understand. <BR> <BR>I'm very glad you're still feeling better. I will keep my fingers crossed that it continues! <BR><BR>[Guest Posted by: 'Lauren']

Guest

Postby Guest » Sun Oct 07, 2001 7:19 am

Hello, <BR>Thank you all for being here and many thanks to the creators of this web site. This board is great! <BR>I got CDiff about 3 months ago from Clyndamycin given to me (probably unnecessarily) during a normal uncomplicated labour. I went to the hospital perfectly healthy and fit to give birth and came home with this horrible thing (and of course a sweet little baby <IMG SRC="http://www.cdiffsupport.com/discus/clipart/happy.gif" ALT=":)" width="15" height="15"> ) <BR>You can probably guess the rest...a horrible week of intense diarrhea, running back and forth to the family doctor and ER (just to be told "it's probably viral"), trying to breastfeed while fighting dehydration... until they finally diagnosed it. <BR>I had about 7 weeks of Metronidazole (various regimes) and it probably just killed off any remaining friendly bacteria. Then I had a relapse on Vanco (6 days after a 2 week course). After my second 2 week course of Vanco I asked the GI to let me try Lauren's pulse dosing this time. However, he changed it so that I repeat each cycle only twice instead of three times. Also, the pulsing started after 2 weeks of Vanco (as opposed to a month). <BR>I am worried that it may be too short to have the desired effect...do any of you have an opinion on this? <BR><BR>[Guest Posted by: 'MX']

Guest

Postby Guest » Mon May 19, 2003 7:11 pm

I've read all your mesages and is seriously cinsidering pulse dosing for my husband, since he already had his fifth reoccurence. but, I saw that many of you refer to the article from American Journal of gastroenterology, 'Braking the cycle: tratment strategies for 163 of recurrent clostridium difficile disease", where can I find this article, I really need to read it...

Guest

Postby Guest » Mon May 19, 2003 10:30 pm

Natalia- <BR>You can access the article on the internet in the American Journal of Gastoenterology......volume 97, pages 1769-1775. The name of the article is "Breaking the Cylcle-Treatment Strategies for 163 Cases of Recurrent Clostridium difficile disease." You have to set up password etc. to get in to it. It is an excellent article and good one to take to your doctor.

Guest

Postby Guest » Fri May 23, 2003 11:47 am

Hi, <BR>I am so glad I came across this site. I had a left hip replacement March 3rd. Since the operation I have been in the hospital twice. The doctors kept sending me home. The last time in one doctor said he was going to treat me for c-dif. I had a 2 week dose of Vanco, and seemed to be okay for about 4 days now I've got the diearea again. What is this pulse dosing I have seen talk about? I have a call in to my doctor, but I have to wait for a call back!! <BR>Any help would be apperciated! <BR>Cheryl


Return to “Treatments”



Who is online

Users browsing this forum: No registered users and 16 guests