Have you taken an antibiotic w/Dificid at the same time for prevention?

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Ygy
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Joined: Sat Dec 02, 2017 8:25 pm

Have you taken an antibiotic w/Dificid at the same time for prevention?

Postby Ygy » Thu Jul 30, 2020 8:28 pm

Hi!

I have a UTI and need to take Macrobid. I’ve worked with my GI and GYN and they’ve suggested taking Dificid at the same time as I take the antibiotics for hopefully preventing a reoccurrence. As I’m fairly sure I will get another cdiff infection bc of my history which I listed at the bottom of the post.My doctors said to try this approach.

Has anyone successfully prevented cdiff in this way? I read some posters will take Vancomycin concurrently with the antibiotics.


Any success with this or suggestions?? Thank you!


For reference I’m a 34yo female. Here is a brief history of my c diff infections.

1st cdi : I got cdiff in 2012 while working as an RN easily treated with 10 days of vancomycin

2nd cdi: I got cdiff in 2017 after taking Macrobid. Didn’t have classic symptoms at first so I wasn’t tested or treated for a month. Took 10 day vanco. Relapsed 6 week vanco taper. Wasn’t working well so tried Dificid and healed.

3rd cdi: 2018 -Had a csection with my 3rd baby, got vanco IV as infection prophylaxis but still got cdiff after 2 weeks post op. Still not sure if it was hospital acquired or bc of IV vanco. Treated promptly with Dificid which was effective.

georgina
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Re: Have you taken an antibiotic w/Dificid at the same time for prevention?

Postby georgina » Fri Jul 31, 2020 2:21 am

Macrobid is supposed to be on the "safe side". As you know , there is no 100% safe antibiotic , there are just some that are safer the others. If you need to take a course of antibiotics up your probiotic intake and , pray you won't relapse.

Ygy
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Posts: 31
Joined: Sat Dec 02, 2017 8:25 pm

Re: Have you taken an antibiotic w/Dificid at the same time for prevention?

Postby Ygy » Fri Jul 31, 2020 10:26 am

Georgina

Thank you for replying!
Unfortunately I got cdiff from Macrobid 3 years ago. I took florastor with it. I hadn’t been taking florastor previous to my Macrobid use. But I have been on florastor now for the past 3 years, perhaps it will help this time.

I listed my history below my post:)

NanciT
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Re: Have you taken an antibiotic w/Dificid at the same time for prevention?

Postby NanciT » Fri Jul 31, 2020 1:13 pm

Ygy

Sorry you are going through this, it's a worry we all have. I don't know if taking Dificid would make a difference. Dificid is so expensive so I don't believe we have had that question before. It's fortunate it cured you with one round in the past.

My ID would only consider Vanco wen I had to take Keflex in March and unfortunately I did get CDIFF although I took it during and post 5 days.

It was then a battle with my PPO insurance to get a Difcid taper to treat( 2 10 days RX's) but I did finally get it. I am now 12 wks out dealing with Post IBS but getting through. My original infection was 2014/2015.

I find we see more and more nurses on here...wishing you the best with this!

NanciT

DianaLyn
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Joined: Tue Jul 17, 2018 8:32 am

Re: Have you taken an antibiotic w/Dificid at the same time for prevention?

Postby DianaLyn » Sun Aug 16, 2020 6:56 pm

I took Macrobid for a kidney infection with no issue. Lots of kefir, no processed foods and tons of probiotics. I think Macrobid is a very low offender. My ID doc said I'd be fine on it and I was.


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