Question about test results?

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adamvand
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Question about test results?

Postby adamvand » Mon Apr 20, 2020 5:02 pm

Has any of you had a NAAT for C Diff where the presence of the bacteria was positive but the toxin negative? My doctor considered it as a positive test but that still confused me. Anyone else have experienced this?

roy
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Re: Question about test results?

Postby roy » Mon Apr 20, 2020 5:16 pm

If the toxin is negative (and you dont have obvious symptoms) it's a negative test.
Dont trust that Dr!

If the first part of the test was considered reliable there would be no reason to confirm it by doing a toxin test, nobody tests just for fun!
The decision to treat is not made on the first part of the test.

adamvand
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Re: Question about test results?

Postby adamvand » Mon Apr 20, 2020 5:28 pm

roy wrote:
> If the toxin is negative (and you dont have obvious symptoms) it's a
> negative test.
> Dont trust that Dr!
>
> If the first part of the test was considered reliable there would be no
> reason to confirm it by doing a toxin test, nobody tests just for fun!
> The decision to treat is not made on the first part of the test.

Sorry, I forgot to mention, but I did have pretty bad symptoms with it.

roy
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Re: Question about test results?

Postby roy » Mon Apr 20, 2020 6:13 pm

please dont use the quote feature.

If symptoms are copious watery D 3 x a day or more it might still be c.diff but additional testing should be done to confirm it.

beth22
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Re: Question about test results?

Postby beth22 » Mon Apr 20, 2020 9:41 pm

When I have had positive PCR with a negative EIA, the lab labeled it as negative.

adamvand
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Re: Question about test results?

Postby adamvand » Mon Apr 20, 2020 9:43 pm

This is what the laboratory interpretation says;

"Indeterminate interpretation: Clinical evaluation
necessary, may represent colonization if there
is an alternative cause of diarrhea.
May indicate Clostridium difficile infection with a lower
burden of disease or a false negative toxin test.
Caution is advised in immunocompromised patients
or when there is a high suspicion for infection.
Obtain an ID consult if appropriate."

Caligirl
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Re: Question about test results?

Postby Caligirl » Mon Apr 20, 2020 11:37 pm

My first 2 tests were negative for the toxins, but my symptoms were HORRRRRIBLE! My 3rd test (second relapse) both toxins A and B were positive, but my symptoms were mild and were able to be treated only with Florastor.

Ali-Mar
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Joined: Sat Mar 21, 2020 4:17 pm

Re: Question about test results?

Postby Ali-Mar » Wed May 27, 2020 12:53 am

Caligirl, that is very encouraging to see it can be treated with Florastor. What was the dose you were taking to treat the C-Diff?
Male 54, contracted C-Diff on Feb 5, 2020, diagnosed on March 2nd, Took Flagyl for 8 days, Vanco for 10 days, relapsed 5 weeks post-Vanco. finished Dificid Taper on June 20 relapsed two weeks later, had the FMT on July 14th, 2020


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