FMT Capsule G3 using OpenBiome vs colonoscopy route

If you have had or are considering an FMT please share your experiences here.
foots
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FMT Capsule G3 using OpenBiome vs colonoscopy route

Postby foots » Tue Mar 01, 2016 3:48 pm

Has anyone tried the capsule route? I am thinking to do that if I have a relapse, but then I read that it is 70% effective & if you fail it, you must then do 60 more pills over 2 days, then it's 94%. My stomach hurts just thinking about it. Apparently, in the study, the 1 person who still failed it was cured by a traditional FMT.

Thoughts? Experiences? It seems way easier, but somehow I think I'd be in the 30% failure group...hah.

NanciT
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Re: FMT Capsule G3 using OpenBiome vs colonoscopy route

Postby NanciT » Wed Mar 02, 2016 1:12 am

Hi Foots,

My doctor mentioned this to me if I had CDIFF return, she was going to look into it but thankfully all has been well! There was an article posted today in Media, this company was mentioned.
NanciT

beth22
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Re: FMT Capsule G3 using OpenBiome vs colonoscopy route

Postby beth22 » Wed Mar 02, 2016 2:53 am

Personally, I don't think I would do it, but I had two failed NG transfers, so I guess I would not be a good candidate. I also got SIBO and I think part of it was that I had the FMT put into the duodenum. I have read since that the small intestine really should not have the same kind of bacteria as the colon, so I would opt for a colonoscopy or enema transfer. But, there are others who had this done and got better. I would discuss all your options well with your doctor and ask about side effects for each.

roy
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Re: FMT Capsule G3 using OpenBiome vs colonoscopy route

Postby roy » Wed Mar 02, 2016 11:17 am

FDA concerns are that the pills are made with multi doner material and they would like them to be studied as a drug and undergo stringent testing and quality control.
Remember HIV and BSE being passed on by pooled blood products?
Personaly I think a colonoscopy fmt, put into the part of the body that it calls home, from a known single donor seems a lot safer.


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